Principal Investigator

Dr. Justin Parreno

Assistant Professor in Biological Sciences and in Biomedical Engineering
images
  • Natural Sciences and Engineering Research Council of Canada (NSERC) Postdoctoral Fellow, The Scripps Research Institute, La Jolla, California / University of Delaware
  • Ph.D., NSERC Alexander Graham Bell Research Scholar, University of Toronto, Canada
  • M.Sc. Medical Science (Specialization in Bone and Joint Health), University of Calgary, Canada

I have always been intrigued by the structure-function relationship in cells; specifically, how the organization of actin within cells can determine the way cells behave. The actin cytoskeleton was once thought to be difficult to target in disease. But with the increasing understanding of the diversity of actin networks targeting the actin cytoskeleton is now possible. In the lab, we are focussed on targetting the actin cytoskeleton to prevent and treat diseases such as Osteoarthritis and Cataracts.

Outside of the lab, I enjoy early mornings at Lil’ Bob, discovering new coffee shops,
playing and watching basketball, and most importantly spending time with my family and dog.

Staff

Graduate Students

Thomas Manzoni

Ph.D. Student, Biological Sciences

Chemistry-Biology Interface Fellow

images

B.Eng. Mechanical  Engineering, University of Delaware

Hello, my name is Thomas, and I completed my Bachelors of Mechanical Engineering with a concentration in Biomechanics here at the University of Delaware.

In the Parreno Lab, I am currently investigating the use of 3D bioprinting as a method to create bioengineered cartilage with zonal organization. In addition, I work to utilize 3D printing as a method to develop novel devices to mechanically stimulate cells/tissues.

Stephanie Richardson-Solorazano

Ph.D. Student, Biological Sciences

University Graduate Scholar

images

Hi, my name is Stephanie and I am a PhD student with a concentration in molecular biology, biochemistry, and genetics. I completed my undergraduate degree at the University of San Diego in biochemistry while focusing on organometallic research. Once I got out into the workforce I fell in love with the idea of combining chemistry and biology and applied to the University of Delawares biology program. My current research in the Parreno lab focuses on developing an in vitro model of human cartilage to use in drug screening for personalized medicine against Osteoarthritis.

Rylee King

MS Student, Biological Sciences
images

Hello! My name is Rylee King, and I graduated with a Bachelors of Science in Biology/Psychology with a minor in Forensic Science from Loyola University of Maryland in 2023.
I am super excited to join Parreno Lab again. In the summer of 2022, I joined Team Lens through the Delaware INBRE program. I look forward to continuing my research on the lens and how the actin cytoskeleton plays a role in cataracts.
I enjoy going to the beach, boating, and playing with my adopted dog Benny in my free time.

Marin Herrick

MS Student, Biological Sciences
images

Hi! My name is Marin and I graduated from the University of Delaware with a Bachelors in
Biological Science in the spring of 2023. I am thrilled to be working towards my Masters here at
UD and joining the Parreno Lab as part of Team Cartilage.
Under Team Cartilage, I will be using a DMM model to study how F-actin destabilization leads to
cartilage degeneration and cell apoptosis contributing to the progression of post-traumatic
osteoarthritis.
Outside of the lab I enjoy going to concerts, traveling/exploring new places, and riding my
horses.

Undergraduate Students

Carlos (CJ) Benito

Senior Thesis Student, Biological Sciences
images

Carlos Benito was born and raised in New Jersey where he grew up with his three sisters. He is majoring in Biology with minors in Spanish for Healthcare and Entrepreneurship. He is currently working on pursuing an undergraduate thesis in the lab. His current research focuses on different structures within the eye and with a focus on presbyopia and age-related loss of vision. Outside of the lab, he enjoys gardening, repairing antique houses and working as Chief Business officer of Sia Precision Education.

Anh Ho

Undergraduate Student Intern, Biological Sciences
images
My name is Anh Ho, and I am a third-year student at the University of Delaware. I am currently majoring in Biological Sciences (BS) and minoring in Medical Diagnostics on a pre-medical track.
Working alongside Thomas, I am excited to be studying bioengineered cartilage with zonal organization to further the invivo study of actin involvement in cartilage.
Outside of the lab, I am very involved in the APIDA organizations at the University of Delaware, where I am currently President of Asian Awareness and Perspective Connections Magazine and Public Relations Chair of the Vietnamese Student Association. In addition, I enjoy organizing philanthropical events through UD Operation Smile as their Awareness Chair and practicing martial arts in my free time.

Mark Arranguez

Undergraduate Student Intern, Human Physiology
images

Hello! My name is Mark Arranguez and I am a second-year Human Physiology major on the pre-med track at the University of Delaware.

In Parreno Lab, I proudly represent Team Cartilage as I research and explore the cartilage degeneration and death loops caused by F-actin destabilization.

Outside of the lab, I hold the Public Relations position for the Filipino Student Association on the 2023-2024 Executive Board. In my free time, I enjoy going to the gym, traveling, and thrift shopping.

Kaelyn Owen

Undergraduate Student Intern, Bioengineering
images

Hello! My name is Kaelyn Owen and I am an undergraduate student majoring in biomedical engineering with a minor in biochemical engineering. My research focuses on assessing the relationship between mechanical loading, the actin cytoskeleton, and gene regulation of tenocytes. Outside of the lab, I am heavily involved with the UD Cheer Team as a student athlete and with Tau Beta Pi as the Treasurer. I also enjoy spending time with my sisters in Phi Sigma Sigma.

Ashna Patel

Undergraduate Student Intern, Psychology
images

My name is Ashna Patel, and I am a first-year honors student at the
University of Delaware. I am currently majoring in Psychology (BA) on
a pre-medicine track!

Working alongside Stephanie, I am excited to be studying an in vitro
bioengineered articular cartilage model to use for personalized
medicine against osteoarthritis.

Outside of the lab, I am involved with Hugh O’Brian Youth Leadership,
where I am the Director of Programs and a facilitator for Delaware’s
seminar, Delmarva Spine and Pain Clinic, where I am a volunteer
Medical Assistant, and Tri-Beta Biological Honor Society. In addition,
I enjoy volunteering at the hospital, Club tennis, baking, and
spending time with my family and friends!

Lilly Smull

Undergraduate Student Intern, Biological Sciences
images

Hi, my name is Lilly Smull and I am a sophomore at the University of Delaware in the honors college. I am majoring in biological sciences with a concentration in cell and molecular biology and genetics and a minor in forensic science.
In the lab, I work alongside Thomas researching the optimization of superficial zone chondrocyte expansion and redifferentiation, ultimately working towards developing better superficial zone repair tissue.
Outside of the lab, I enjoy photography and have gotten involved with photography club and UDress magazine as a photographer. I love being outside, hiking, and playing rugby for the university’s women’s club team.

'Paw'reno Lab Members

Winston Pawreno

Lab manager
images

My name is Winston. I ruff walks.

Max Manzoni

3D Pawrinter Operator
images

I chase chickens.

*No relation to Max Schofield*

Cinnamon and Beauty Benito

Interns
images

We are entre’paw’neurs like our dad

Max Barndt

Ambassador
images

My name is Max, I collaborate with the ‘Paw’reno lab and I am the Parreno-Fowler lab relations officer.

Benny King

Ambassador
images

Alumni

Name Position Current Position
Mara Cripsin Undergraduate Researcher Medical Student, Philadelphia College of Osteopathic Medicine
Marissa Heino Undergraduate Researcher Engineer, Cytiva
Lucas Mennetti PhD Student Pequea Valley Exteriors
Sohan Shah Undergraduate Summer Researcher Medical Student, Sidney Kimmel Medical College
Jonah Hammerstedt Undergraduate Researcher
Arya Faghri Undergraduate Student Intern Undergraduate Student (Biology), University of Delaware
Kameron Inguito Undergraduate Researcher Medical Student, Sidney Kimmel Medical College
Emily Molczan Undergraduate Researcher Project Manager, Epic Systems
Jennifer Schiffel High School Capstone Project Nursing Student, Fairfield University
Kaitlyn D’Aurizio High School Capstone Project Undergraduate Student (Health Science), Quinnipiac University
Aarav Patel High School Capstone Project Undergraduate Student (Biology), Drexel
Mandy Schofield MS Student Staff Scientist, Kaztronix LLC
Emily Yontas Undergraduate Student Intern
Grace Emin MS Student Field Scientist, Denovix
Sofia Gonzalez-Nolde MS Student Research Associate, University of Michigan
Zsanaia Badiang Undergraduate Student Intern
Paulina Hammond Undergraduate Student Intern
Alexandra Schaffer Undergraduate Student Intern
Alissa Rzepski Senior Thesis Student
Tori Reiner Research Assistant
Cameron Schweiger Undergraduate Student Intern
Valerie West Undergraduate Student Intern
Matthew Ebron Undergraduate Student Intern
Bryce Lesko Summer Intern